Breakthrough Study of the Clock to Predict Lifespan

  • The study focused on the DNA methylation process.
  • The average life of early humans used to be 38 years.
  • It is predicted that in this century the longest life expectancy will be in Spain.

A new study has been published pertaining to the predicting the lifespans in species. The Australian scientists from SCIRO developed the clock of lifespan. The Commonwealth Scientific and Industrial Research Organization is an Australian federal government agency responsible for scientific research. Its chief role is to improve the economic and social performance of industry for the benefit of the community. CSIRO works with leading organizations around the world. The clock allows them to calculate these of living and even dead species.

Diagram Source: uluc.edu

During each lifespan we experience changes, some gene activities decrease and some increase. The DNA methylation process is when the DNA molecule is modified without changing the nucleotide sequence of the DNA itself. DNA methylation is a process by which methyl groups are added to the DNA molecule. Methylation can change the activity of a DNA segment without changing the sequence. When located in a gene promoter, DNA methylation typically acts to repress gene transcription. Also, two of the DNA bases can be methylated. Over 60% of human protein coding genes contain a CGI in the promoter and can potentially be regulated by DNA methylation. Methyl labels are epigenetic markers that can indicate the most diverse features of the body and its biological age. Epigenetics is the study of heritable changes in gene expression in active versus inactive genes.

The Australian scientists specifically focused on the density of the so-called methylation points and discovered a correlation with life expectancy. The team studied and tested over 252 types of species. The Artificial Intelligence algorhytm specifically created for the study had close to 30,000 areas of DNA, eventually narrowing down the markers to 42.  There after the formula was created to provide an accurate prognosis of lifespan.

It was discovered that early humans had a lifespan of only 38 years. For now, the new method can only be applied to the whole breed of species and not each individual species. However, it would allow scientists to learn that if the species do not live their predicted lifespan, than it means ecology and other environmental factors contributed to the shorter life.

Overall, given a myriad of the studies, human life is supposed to increase in the latter half of this century in the West. Spain is expected to have the longest life expectancy in the world. Japan is second. However, in Middle Eastern nations lifespan are decreasing. One of the main factors contributing to life expectancy increases in humans is the ability to grow organs and the transplant industry, including breakthrough medical discoveries.

DNA is the vital information in all living organisms and understanding fully everything it has to offer unlocks the future.

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Christina Kitova

I spent most of my professional life in finance, insurance risk management litigation.

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