In the protein-protein interaction or PPIs process, it is necessary for the proteins participating in undergoing a type of modification. Several protein-centric pharmaceuticals evolve their therapeutic and analgesic properties and effects from specific changes.
It is essential to understand that the effects of the modifications are critical to the leading molecules’ selection and design. Most of the time, ways that evaluate and introduce the alterations of protein vary. The processes and techniques mentioned in this article show that several researchers are working on certain levels to bring out favorable results. While some of them are blending proteins with proteins’ fragments through molecular tethers, others are integrating functional and biophysical ways of approach.