Cov kws tshawb fawb hauv Lavxias Kev Kho Mob Cancer Tshiab Siv Nanotechnology

  • Cov kws tshawb fawb hauv Lavxias siv hyperthermia tshav kub los kho mob qog nqaij hlav.
  • Cov kev tshawb fawb siv nanatechnology los kho mob qog noj ntshav tau nyob ib puag ncig rau ntau kaum xyoo.
  • Cov txheej txheem tsis tau zoo tag nrho raws li tseem.

Cov kws tshawb fawb hauv Lavxias tau muab tsab ntawv tshawb fawb tshiab thov tias kho tus mob hnyuv loj dua. Qhov tshiab ib feem ntawm kev kho cov txheej txheem suav nrog siv hyperthermia-cua sov ntawm qhov kub thiab txias los ntawm nanoparticles. Cov tshuaj yog raws li cobalt ferrite (CoFe2O4) nanoparticles, lub zog sib nqus cov khoom uas muaj kev sib zog siab thiab nruab nrab hlau nplaum. Qhov lus hais yuav tsum yog tus sau xwb, ntawm theem ntshiab, muaj kev sib zog ua kom muaj zog thiab nruab nrab hlau nplaum.

Txoj kev soj ntsuam siv nas.

Sib nqus hyperthermia yog ib txoj hauv kev tshiab ntawm kev kho mob qog ntshav uas kub hnyav tuaj yeem ua rau cov roj ntsha tsis ua haujlwm, uas ua rau cov qog ua kom sai. Cov ntaub ntawv tshawb fawb hais txog cov ntawv thov no tau dhau los ua txij li xyoo 2010, tab sis cov hau kev no tseem tsis tau ua tiav tas li.

Sib nqus hyperthermia (MHT) yog ib hom kev kho mob qog ntshav uas ua kom zoo dua ntawm cov cua sov tsim los ntawm cov hlau nplaum nanoparticles. MHT tau tshawb nrhiav ntau yam thoob plaws hauv tswv yim thiab kev sim ua kom ncav cuag kev kho kom tau txiaj ntsig. Kev ua kom muaj MNPs nyob sib sib zog nqus rau hauv cov ntaub so ntswg lossis cov plab hnyuv siab raum los ntawm MHT tuaj yeem ua tiav ntawm zaus (f) thiab teb (H) uas tsis ua mob rau tib neeg lub cev (H xf ≤ 5 × 108 A / ms).

Txawm li cas los xij, txhawm rau tiv thaiv kev tuag ntawm cov nqaij hauv lub cev kom noj qab haus huv nrog rau cov neeg mob, txoj kev cuam tshuam nrog kev xaiv cov lus xaiv ntawm tus neeg sawv cev nrog cov khoom sib nqus ua rau cov qog. Vim tias lawv, nws muab cov ntawv hauv zos thiab tswj cov cua sov nyob ib puag ncig ntawm qhov chaw xaiv hluav taws xob. Tus neeg sawv cev (hauv nws lub luag haujlwm yog nanoparticles ntawm cov hlau oxides) tiv tauj nrog cov qog hlwb thiab hauv qab ntawm kilohertz hloov hluav taws xob hauv cheeb tsam hluav taws xob tau rhaub, rhuav tshem lawv.

Daim duab tshawb nrhiav ntawm kev kho mob.

Cov thev naus laus zis tsis tau nce mus rau cov ntsiab thiab tsim kab mob qog noj ntshav. Cov kws tshawb nrhiav tseem tab tom tshawb nrhiav cov khoom tsim nyog los siv thiab ntsuas kub kom zoo kom ua tiav cov txiaj ntsig zoo tshaj plaws.

Cov kws tshawb nrhiav Lavxias tau tuaj yeem ua tiav cov kev ploj ntawm malignancies hauv 100% ntawm cov nas uas muaj mob qog nqaij hlav tom qab ua kom sov lub qog ntawm qhov kub ntawm 41-43 ° C. Cov kws tshawb fawb tau siv cobalt ferrite nanoparticles, uas muaj lub zog sib nqus, thiab yog li muaj peev xwm muab cov cua sov ntawm cov hlwb thiab cov ntaub so ntswg nyob rau hauv ntau qhov kub ntawm cov lus teb rau qhov cuam tshuam ntawm hluav taws xob teb. Tsis tas li ntawd xwb, lawv muaj kev ruaj khov nyob rau hauv kev mob tshwm sim hauv lub cev, tsis muaj qhov cuam tshuam ntawm lub hlwb thiab cov ntaub so ntswg ntawm lub cev, thiab lawv tuaj yeem yooj yim thiab pheej yig tau txais.

Tom qab ntawd, cov kws tshawb nrhiav tau ua qhov kev sib piv ntawm qhov cuam tshuam ntawm kev hloov sib txawv ntawm ob tus qauv ntawm cov hlav qog hlav-tsis mob hnyav thiab "ua phem" nquag metastasizing– thiab pom tias cov qog nqaij hlav hauv lub cev yog qhov nkag siab ntau dua rau hyperthermia thiab tuag thaum lub sijhawm sov li ntawm 41 -43 ° C.

Raws li cov ntaub ntawv luam tawm, mob cancer ntawm lub mis tau muaj kev tiv thaiv tshav kub ntau dua thiab cov qog nqaij hlav cancer tuag ntawm hyperthermia> 47 ° C. Hauv cov pawg ntawm cov tsiaj uas tau kho nyob ntawm 46-48 ° C thiab 58-60 ° C, kev muaj sia nyob yog 25-40%. Txawm li cas los xij, ib qho tseem ceeb tshawb pom yog qhov tseeb hais tias kev kho mob nrog sib nqus hyperthermia ua rau kev txo qis hauv cov tshwm sim ntawm cov kabmob metastases hauv lub cev ntawm cov tsiaj piv rau kev phais mob qog.

Cov kws tshawb fawb hauv Lavxias tseem txuas ntxiv ua lawv txoj hauv kev tshiab rau kev kho mob cancer no.

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Xa Koj Qhov Ntawm No

Christina Kitova

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